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Vol. 34, No. 8(3), S&M3042

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Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
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Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
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Sensors and Materials, Volume 33, Number 10(3) (2021)
Copyright(C) MYU K.K.
pp. 3635-3643
S&M2714 Research Paper
https://doi.org/10.18494/SAM.2021.3589
Published: October 29, 2021

Novel Photothermal Aptamer-based Sensing System for Highly Ultrasensitive Detection of Ochratoxin A [PDF]

Pinzhu Qin, Ying Guan, and Yige Qiu

(Received August 18, 2021; Accepted September 29, 2021)

Keywords: aptamer, linear range, nanoparticles, ochratoxin A, temperature

We developed a photothermal sensing system based on the photothermal effect of the Tetramethyl benzidine/Hydrogen Peroxide (TMB-H2O2) colorimetric system mediated by Fe3O4 nanoparticles. The ochratoxin A (OTA) aptamer can bind OTA particles with high affinity and specificity. The charge transfer complex of the single electron oxidation product of TMB (oxidized TMB) acts as a photothermal probe to convert the recognition signal into heat, allowing sensitive and quantitative photothermal detection using only a thermometer. In the proposed sensing system, the temperature change varied with the concentration of OTA. The aptamer-based sensing system provides a wide detection range for OTA from 0.25 nM to 2500 μM. We provide a new approach for the detection of mycotoxins because of the advantages of the simple readout method, low sample consumption, and lower detection cost.

Corresponding author: Pinzhu Qin


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This work is licensed under a Creative Commons Attribution 4.0 International License.

Cite this article
Pinzhu Qin, Ying Guan, and Yige Qiu, Novel Photothermal Aptamer-based Sensing System for Highly Ultrasensitive Detection of Ochratoxin A, Sens. Mater., Vol. 33, No. 10, 2021, p. 3635-3643.



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