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Notice of retraction
Vol. 34, No. 8(3), S&M3042

Notice of retraction
Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
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Sensors and Materials, Volume 35, Number 4(2) (2023)
Copyright(C) MYU K.K.
pp. 1293-1299
S&M3246 Research Paper of Special Issue
https://doi.org/10.18494/SAM4164
Published: April 11, 2023

Engineering Oral Microenvironments Using Microphysiological Systems [PDF]

Yuji Nashimoto, Takeshi Hori, Serge Ostrovidov, Sayaka Katagiri, and Hirokazu Kaji

(Received October 7, 2022; Accepted November 17, 2022)

Keywords: microphysiological system, organ-on-a-chip, oral microenvironment, microfluidic device

A deeper understanding of oral homeostasis and a precise evaluation of the effects of foreign materials are crucial for the oral health and total quality of life. Microphysiological systems (MPSs) or organs-on-chips have emerged over the past decade as attractive tools for emulating the physiological functions of organs in vitro. An MPS can pattern cells and matrices in a tiny microfluidic chip, which realizes in vivo-like cellular interactions and biochemical and physical forces. From this review, we summarize recent developments in MPSs that mimic the oral microenvironment. Oral MPSs can effectively evaluate the toxicity of dental materials in the oral cavity and recapitulate morphogenesis in the oral microenvironment. Oral MPSs are valuable tools for screening dental materials and understanding the development of oral tissues.

Corresponding author: Yuji Nashimoto, Hirokazu Kaji


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Cite this article
Yuji Nashimoto, Takeshi Hori, Serge Ostrovidov, Sayaka Katagiri, and Hirokazu Kaji , Engineering Oral Microenvironments Using Microphysiological Systems, Sens. Mater., Vol. 35, No. 4, 2023, p. 1293-1299.



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